题目内容

Which protein with mutations in its gene could not inducedrug resistance?

A. porin in the outer membrane;
B. P12 of 30S ribosome ,
C. β-unit of RNA polymerase ;
D. lipoprotein in cell wall.

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Which mechanism will confer sulfonamide resistance in thebacteria?

A. Bacteria absorb folic acid from the environment;
Bacteria alter P12 of 30S ribosome ,
C. Bacteria with mutatedβ-unit of RNA polymerase ;
D. Bacteria produce beta-lactamases.

Which statement about efflux pumps of bacteria is not right?

An efflux pump is a membrane active protein.
B. An efflux pump works without consumption of ATP.
C. Efflux pumps can pump more than one type of antimicrobials out of a cell.
D. Efflux pumps can confer multi-drug resistance to bacteria.

Which is not the biochemical mechanisms of antibiotics-resistance?

A. Barriers formed to block accumulation of antibiotics in bacterial cells;
Bacteria produce enzymes which can break the structures of antibiotics;
C. The bacterial molecules surround the antibiotics of penetrating the cells;
D. Bacterial Ribosome protein mutated so that antibiotics can not bind them.

Which molecule mutated or decreased at level will develop drug-resistance?

A. peptidoglycan,
B. hemolysin
C. Protein porin channels in outer membrane
D. M protein in the cell wall.

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