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The team led by Kathy Niakan at the Francis Crick Institute in London used CRISPR-Cas9 to switch off a particular gene involved in embryo development, known as OCT6. Blocking the functioning of this gene means the resulting protein, also called OCT6, cannot be produced, eventually halting an embryo's development.
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The team led byJunjiu Huang at Sun Yat-Sen Universityattempted to modify the gene HBB responsible for β-thalassemia, using CRISPR/Cas9. HBB encodes the β-globin protein. Mutations in the gene are responsible for β-thalassemia.
Researchers in China have reported editing the genes of human embryos to try to make them resistant to HIV infection, published in J Assist Reprod Genet (2018) used CRISPR-editing tools in non-viable embryos that were destroyed after 3 days.
当地下室顶板是框架柱的嵌固部位时，则地下室顶板以下部分的柱端箍筋（ ）。
板内纵向钢筋采用绑扎搭接连接时,接头处钢筋又以是非接触方式,但搭接部位钢筋净距不宜小于( )。
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