Purines and pyrimidines are:
A. Dietary essential
B. Dietary nonessential
C. Derived from essential fatty acids
Derivatives of essential amino acid
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Which statement for purine biosynthesis is incorrect?
A. Requires vitamin B12
B. Assembled on ribose phosphate
C. Requires PRPP
D. Requires glycine
Nitrogen or carbon atoms are contributed to the structure of the purine ring by amino acids, except:
A. Glycine
B. Glutamine
C. Aspartate
D. Glutamate
Lesch-Nyhan syndrome may lead to:
A. Self-destructive behavior
B. Gout
C. Elevated levels of PRPP
D. All of the above
Lesch-Nyhan syndrome is due to the lack of:
A. HGPRTase
B. APRTase
C. Adenosine deaminase
D. PRPP amidotransferase