Which of the following factors will reduce a drug’s bioavailability?
A. incomplete dissolution
B. degradation by stomach acid
C. poor ability to go across cell membrane due to low hydrophobicity
D. poor dissolving in the stomach or small intestine due to low hydrophilicity
E. all of the above
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Syrups and elixirs contain ethanol to______.
A. increase the solubility of aromatic drug substance
B. kill microorganisms in the drug product
C. form heterogeneous mixture
D. make the drug more attractive to patients
Which of the following inactive ingredients can prevent the growth of microorganisms in a solution?
A. stabilizer
B. preservative
C. flavorant
D. solvent
Which of the following dosage forms is given parenterally?
A. powder for injection
B. chewable tablet
C. syrup
D. oral solution
Dissolution refers to _________.
A. release of drug molecules from the surface of the solid drug and subsequent dissolving in the surrounding body fluid
B. drug movement through the GI tract
C. drug absorption into the blood
D. disintegration of solid dosage form into smaller pieces or particles.