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Important milestones in parts and circuit design in E. coli continued to emerge during 2004-2007, including DNA-based systems that expanded synthetic circuit design from mainly transcriptional control into post-transcriptional and translational control mechanisms.
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On July 9-10, 2009, the US National Academies;s Committee of Science, Technology and Law convened a symposium on "Opportunities and Challenges in the Emerging Field of Synthetic Biology."
In 2015, the Chinese government released a national strategic roadmap on synthetic biology. The roadmap specifies a timeframe for research on synthetic parts, commercial application of engineering parts, and clinical application of devices and systems for the next 5, 10, and 20 years.
Post-translational control systems began to appear during 2008-2013. Synthetic protein scaffolds were used to introduce new circuit feedback connections in order to predictably alter the dynamic behaviour of a native yeast mitogen-activated protein (MAP) kinase pathway.
On March 13, 2018, over 100 environmental and civil society groups, including Friends of the Earth, the International Center for Technology Assessment (ICTA) and the ETC Group issued the manifesto the Principles for the Oversight of Synthetic Biology.
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