Whichofthefollowingstatementsabout non-viralvectorsforgenetherapyarecorrect?

A. Non-viral methods present certain advantages over viral methods, such as large scale production and low host immunogenicity.
B. However, non-viral methods initially produced lower levels of transfection and gene expression, and thus lower therapeutic efficacy.
C. Later technology remedied this deficiency.
D. Methods for non-viral gene therapy include the injection of naked DNA, electroporation, the gene gun, sonoporation, magnetofection, the use of oligonucleotides, lipoplexes, dendrimers, and inorganic nanoparticles.