Which of thefollowingdiseases havebeentestedforgenetherapyinpatients?
A. X-linkedseverecombinedimmunedeficiency(X-SCID)
B. SCIDlinkedwithdeficiencyofadenosinedeaminase(ADA-SCID)
C. lipoproteinlipasedeficiency(LPLD)
D. Leber'scongenitalamaurosis(LCA)
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Which of thefollowingdiseases havebeentestedforgenetherapyinpatients?
A. Wiskott-Aldrich syndrome
B. hemophilia B
C. cystic fibrosis
D. sickle cell disease
Whichofthefollowingdiseaseshavebeentestedforgenetherapyinpatients?
A. muscular dystrophy
B. β-thalassemia
C. Parkinson's disease
D. cancers
Whichofthefollowingdiseaseshavebeentestedforgenetherapyinpatients?
A. α1-antitrypsin deficiency
B. Stargardt disease
C. lung cancer
D. Leber congenital amaurosis
Which of the following statements about the doses ofImlygic are correct?
A. The total injection volume for each treatment by Imlygic visit should not exceed 4 ml for all injected lesions combined.It may not be possible to inject all lesions at each treatment visit or over the full course of treatment.
B. Previously injected and/or uninjected lesion(s) may be injected at subsequent treatment visits.
C. The initial recommended dose is up to 4 ml of Imlygic at a concentration of 10^6 (1 million) PFU per ml.
D. The recommended dose for subsequent administrations is up to 4 ml of Imlygic at a concentration of 10^8 (100 million) PFU per ml.
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