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The size and scope of the synthetic biology field began to increase dramatically in the mid-2000s. The first international conference for the field, Synthetic Biology 1.0 (SB1.0), was held in the summer of 2008 at MIT.
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Important milestones in parts and circuit design in E. coli continued to emerge during 2004-2007, including DNA-based systems that expanded synthetic circuit design from mainly transcriptional control into post-transcriptional and translational control mechanisms.
On July 9-10, 2009, the US National Academies;s Committee of Science, Technology and Law convened a symposium on "Opportunities and Challenges in the Emerging Field of Synthetic Biology."
In 2015, the Chinese government released a national strategic roadmap on synthetic biology. The roadmap specifies a timeframe for research on synthetic parts, commercial application of engineering parts, and clinical application of devices and systems for the next 5, 10, and 20 years.
Post-translational control systems began to appear during 2008-2013. Synthetic protein scaffolds were used to introduce new circuit feedback connections in order to predictably alter the dynamic behaviour of a native yeast mitogen-activated protein (MAP) kinase pathway.
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