Which type of point mutation in chromosomal gene is less likely to alter pore proteins to prevent the entry of drug into cytoplasm.
A. silent mutation;
B. missense mutation,
C. nonsense mutation;
D. Frameshift insertion.
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Which protein with mutations in its gene could not inducedrug resistance?
A. porin in the outer membrane;
B. P12 of 30S ribosome ,
C. β-unit of RNA polymerase ;
D. lipoprotein in cell wall.
Which mechanism will confer sulfonamide resistance in thebacteria?
A. Bacteria absorb folic acid from the environment;
Bacteria alter P12 of 30S ribosome ,
C. Bacteria with mutatedβ-unit of RNA polymerase ;
D. Bacteria produce beta-lactamases.
Which statement about efflux pumps of bacteria is not right?
An efflux pump is a membrane active protein.
B. An efflux pump works without consumption of ATP.
C. Efflux pumps can pump more than one type of antimicrobials out of a cell.
D. Efflux pumps can confer multi-drug resistance to bacteria.
Which is not the biochemical mechanisms of antibiotics-resistance?
A. Barriers formed to block accumulation of antibiotics in bacterial cells;
Bacteria produce enzymes which can break the structures of antibiotics;
C. The bacterial molecules surround the antibiotics of penetrating the cells;
D. Bacterial Ribosome protein mutated so that antibiotics can not bind them.
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