题目内容

RNA-based circuit engineering also underwent an expansion during 2008-2013, as biosensing functions gave way to RNA-based computation. RNA devices were built to control the regulatory logic of gene expression, and RNA design tools were developed to enable the precise, predictable control of heterologous and ____________________________.

查看答案

搜索结果不匹配？点我反馈

更多问题

The CRISPR–Cas immunity system in bacteria and archaea was re-purposed to enable genome-wide transcriptional control. Type II CRISPR–Cas systems use RNA-directed DNA binding by the nuclease Cas9 to detect and cleave invading bacteriophage and other __________________________, and independent groups developed Cas9 nuclease mutants that enable RNA-directed DNA binding by Cas9 without subsequent DNA cleavage.

The report "Synthetic Biology" was submitted to the US Congress by the US Department of Energy in ______. Three technical challenges in the synthetic-biology field were formulated: i) Genome scale engineering tools, DNA synthesis and assembly, and analytical tools; ii) Biological design principles, genetically tractable organisms/chassis, a minimal cell and in vitro systems, tools for plant systems, and biocontainment mechanisms; and iii) Computational tools, information standards, and databases.

In May 2014, researchers announced that they had successfully introduced two new ______________________ into bacterial DNA. By including individual artificial nucleotides in the culture media, were able to exchange the bacteria 24 times; they did not generate mRNA or proteins able to use the artificial nucleotides. The remarkable efficiency of the system and its ability to generate unmarked genomic mutations has the potential to transform bacterial and yeast genetics in the years to come.

In ______, rapid, low-cost detection of Ebola viruses has been achieved by implementing biosensor gene networks on paper.