The half-life of the drug that is suitable for the preparation of sustained/controlled-release preparations is
A. <1 h
B. 2-8 h
C. 24-32 h
D. >48 h
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The dosage of drug for a general preparation is 3 times a day, 100mg each time. Now you are plan to design a sustained-relese preparation, and take medicine once a day. What dosage should you choose?
A. 150mg
B. 200mg
C. 250mg
D. 300mg
E. 350mg
A drug is absorbed in stomach and small intestine, now we plan to deisgn a sustain-release preparation, how long is the proper interval to take medicine?
A. 6h
B. 12h
C. 18h
D. 24h
E. 36h
Compare with general preparations, thebioavailability for sustained/controlled should be in the range of
A. 80-100%
B. 100-120%
C. 80-125%
D. 90-110%