超星 - 第十一章缓控释 - 查题吧

单选题

Which one of the following is not the physical and chemical factors affecting the design of oral sustained and controlled release preparations.

A. stability
B. Water solubility
C. Partition coefficient
D. half-life
E. PKa

单选题

The half-life of the drug that is suitable for the preparation of sustained/controlled-release preparations is

A. <1 h
B. 2-8 h
C. 24-32 h
D. >48 h

单选题

The dosage of drug for a general preparation is 3 times a day, 100mg each time. Now you are plan to design a sustained-relese preparation, and take medicine once a day. What dosage should you choose?

A. 150mg
B. 200mg
C. 250mg
D. 300mg
E. 350mg

单选题

A drug is absorbed in stomach and small intestine, now we plan to deisgn a sustain-release preparation, how long is the proper interval to take medicine?

A. 6h
B. 12h
C. 18h
D. 24h
E. 36h

单选题

Compare with general preparations, thebioavailability for sustained/controlled should be in the range of

A. 80-100%
B. 100-120%
C. 80-125%
D. 90-110%

1