Which of the following would most probably follow the last sentence of this passage？

A. Furthermore, the disappearance of H. pylori may be a sentinel indicating the possibility of other microbial extinctions as well.
B. The possibility that this bacterium may actually protect people against disease of the esophagus has significant implications.
C. However, there has been an unexpected rise in the incidence of a new class of diseases involving the esophagus.
D. The rise of these diseases has occurred just as H. pylori has been disappearing, and it is tempting to associate the two phenomena.