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Passage FourThe "issues" reported were unthinkable. The physician who enrolled the most patients in the study, an Alabama weight-loss doctor, allegedly forged scores of signatures, enrolling "’volunteers" every few minutes. By the time of the FDA review, she was under criminal investigation. (She’s now in federal prison.) Another key researcher had been put on probation by the California medical board for gross negligence. He was arrested shortly after the study ended, when police, called to his home on a domestic violence complaint, found him with a bag of cocaine and waving a loaded gun at imaginary people. The study was so riddled with fraud and error that FDA reviewers decided it was useless. Yet Dr. Ross says he was told to reveal nothing about those problems to the advisory board, which recommended that the drug be approved. Later, he says, he was pressured to soften his report about Ketek’s liver toxicity to gain approval of higher-ups. Six million Americans have now used the drug, including hundreds of infants in a clinical trial designed to test Ketek’s effectiveness against ear infections. "How does one justify balancing the risk of fatal liver failure against one day less of ear pain" one FDA scientist, Rosemary Johann-Liang, protested--to no avail--in a memo to her superiors. Most ear infections clear up in a few days on their own, she says. The agency says the controversy is overblown. "There was enough good, solid scientific data to make that decision." Says FDA spokeswoman Julie Zawisza, pointing to what appeared to be a history of safe use of Ketek in other countries. Ketek has now been linked to 18 deaths and at least 134 cases of liver damage, according to an independent analysis using FDA data. The real toll, some researchers say, may be far greater. Last October the FDA sent a warning letter to Sanofi-Aventis, Ketek’s maker, accusing the company of knowingly presenting compromised data to the agency, a charge the company denies. "We were not aware of the fraud," says spokeswoman Melissa Feltmann. "It was not until the FDA’s criminal investigators uncovered it that we became aware of it." The question remains, What did the FDA and the drugmaker know about the fake safety data, and when Congressmen John Dingell and Bart Stupak, both Michigan Democrats, are investigating that mystery right now in Congressional hearings. "Unfortunately," Stupak says, "the truth comes too late for some victims." According to Paragraph 1, the Alabama physician was accused of（）
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Passage TwoModern Japan, despite its ready adoption of Western manners, is in things theatrical still faithful to the ancient feudal day. It is true that within the last few years, the old school drama has to some extent lost ground, and quite recently performances of Shakespeare’s Othello and Hamlet, and Daudet’s Sappho have been received with favor by Tokyo audiences. The explanation of this curious survival of the old form of play, at a time when all Japan is eagerly imitating the foreigner, is undoubtedly to be found in the peculiar customs of the country. The progressive Japanese finds it easier to change his mode of dress than to reform habits bred in the bone. The old plays, lasting, as they formerly did, from early morning until nearly midnight, just suited the Japanese play-goer, who, when he does go to the theatre, makes an all-day affair of it. Indeed, theatre-going in Japan is a very serious matter, and not to be entered upon lightly or without due preparation. Recently Sada Yoko and Oto Kawakami, who learned a good deal in their foreign travels, introduced the comparatively short evening performance of three or four hours, an innovation which was at once welcomed by the better class of people. But the new arrangement found little favor with the general public, and particular indignation was aroused in the bosom of the Japanese Matinee Girl who loves to sit in the theatre as long as possible and weep over the play. For, to the young gentlewoman, the theatre is essentially the place for weeping. Japanese girls are extremely sentimental, and a play without tear-provoking situations would not appeal to them in the least. The Japanese women are passionately devoted to the drama. It is usual for a party to book a box through a tea house connected with the theatre and at the same time make arrangements for what refreshments they wish served. The Japanese maiden makes the most elaborate preparations days beforehand. To be at the theatre on time, playgoers must rise with the sun, and all their meals, including breakfast, are eaten in the tiny box in the playhouse. It is not an easy task to reach one’s seats and once the family has settled down, nothing but a catastrophe would induce it to leave its box. The women chew candy and the men freely drink sake as the play goes on. As playgoers, compared with Japanese men, Japanese women seem to be all the more（）
个体的意志行动受到无法克服的干扰，预定目标无法实现时所产生的一种紧张状态和情绪体验，这就是所谓的（）。
The concept captured the zeitgeist of the personal computer revolution. Many young people, especially those in the counterculture, had viewed computers as instruments that could be used by Orwellian governments and giant corporations to sap individuality. But by the end of the 1970s, they were also being seen as potential tools for personal empowerment. The ad cast Macintosh as a warrior for the latter cause—a cool, rebellious, and heroic company that was the only thing standing in the way of the big evil corporation’s plan for world domination and total mind control. Once again Jobs would end up suffering bad publicity without making a penny. Apple’s stock price kept dropping, and by March 2003 even the new options were so low that Jobs traded in all of them for an outright grant of $ 75 million worth of shares, which amounted to about $ 8.3 million for each year he had worked since coming back in 1997 through the end of the vesting in 2006. The laws governing such backdating practices were murky, especially since no one at Apple ended up benefiting from the dubiously dated grants. The SEC took eight months to do its own investigation, and in April 2007 it announced that it would not bring action against Apple "based in part on its swift, extensive, and extraordinary cooperation in the Commission’s investigation [and its] prompt self-reporting. " Although the SEC found that Jobs had been aware of the backdating, it cleared him of any misconduct because he "was unaware of the accounting implications." The SEC did file complaints against Apple’s former chief financial officer Fred Anderson, who was on the board, and general counsel Nancy Heinen. Anderson, a retired Air Force captain with a square jaw and deep integrity, had been a wise and calming influence at Apple, where he was known for his ability to control Jobs’ tantrums. He was cited by the SEC only for "negligence" regarding the paperwork for one set of the grants (not the ones that went to Jobs), and the SEC allowed him to continue to serve on corporate boards.
Time for another global-competitiveness alert. In the Third International Mathematics and Science Study--which last year tested a half-million students in 41 countries- American eighth graders 21 below the world average in math. And that’s not even 22 part. Consider this as you try to 23 which countries will dominate the technology markets of the 21st century: the top 10 percent of America’s math students scored about the same as the average kid in the global 24 , Singapore. It isn’t exactly a news flash these days 25 Americans score behind the curve on international tests. But educators say this study is 26 because it monitored variables both inside and outside the classroom. Laziness- the factor often 27 for Americans’ poor performance--is not the culprit here. American students 28 spend more time in class than pupils in Japan and Germany. 29 , they get more homework and watch the same amount of TV. The problem, educators say, is not the kids but a curriculum that is too 30 . The study found that lessons for U.S. eighth graders contained topics mastered by seventh graders in other countries. Teachers actually agree that Americans need to 31 their kids to more sophisticated math earlier. Unfortunately, experts say, the teachers don’t recognize that 32 these concepts are taught is as important as the concepts themselves. Most educators rely 33 on textbooks and rote learning (死记硬背) . While many textbooks cover 34 ideas, most do so superficially, 35 students with the techniques but not the mastery of the broader principles. 28（）
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