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5. a disease of the brain that affects especially old people and results in the gradual loss of memory, speech, movement, and the ability to think clearly

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6. in the end; finally

7. to cause something to break suddenly and violently into small pieces; destroy something completely

8. to overpower somebody or something by force of numbers; defeat

9. a detectable substance that indicates that a particular process or event (for example, glucose metabolism) is taking place

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