Which of following statements about the pharmacodynamic characteristics of aminoglycosides is INCORRECT? ()
A. Cmax/MIC should achieve between 8 and 12.
B. Lower concentrations do increase efficacy.
C. Single daily dose optimal to increase aminoglycoside activity.
D. Monitoring of Cmin is advocated to minimize drug side effects.
E. Significant PAE.
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Which of the following antibacterial drugs should NOT be used during pregnancy? ()
A. Metronidazole
B. Tetracyclines
C. Rifampin
D. Ticarcillin
E. All of the above
Which of the following statements about lipoglycopeptides (Telavancin, dalbavancin, oritavancin) is INCORRECT? ()
A. Structural similar to vancomycin.
B. Sharing the same action mechanism with vancomycin.
C. Bacteriostatic agents.
Dimerization and anchoring to bacterial cell walls.
E. Antibacterial efficacy best correlated to AUC:MIC ratios.
Which of the following is NOT the role of pharmacists in preventing adverse drug reactions? ()
A. Modify the wrong prescription by themselves.
B. Monitor the drug therapy.
C. Identify and assess adverse drug reactions.
D. Record the identified adverse drug reactions.
E. Report the confirmed adverse drug reactions
In general, which of the following is NOT one of the goals of treatment for chronic heart failure? ()
A. To reverse the remodeling of the cardiac structure.
B. To relieve symptoms.
C. To improve quality of life.
D. To delay progression of the disease.
E. To reduce hospitalization and mortality.
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