题目内容

抗生素的应用原则中，下列错误的是

A. 药效临床肯定时，一定要考虑价格因素
B. 感染顽固难控时，有必要考虑有效抗生素联合使用
C. 严重感染时，一般是先经验用药，再根据药敏结果调整用药
D. 有时需抗真菌药与抗细菌药一起使用
E. 血培养结果阳性时，必须根据药敏结果选择用药

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