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Case-control study is often used to investigate the previously suspected adverse drug event. ()

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Acute pyelonephritis will definitely result in chronic pyelonephritis. ( )

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Vesicoureteral reflux is a kind of structural abnormality which usually results in recurrent urinary tract infection. ( )

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The patients with acute coronary syndrome are at high risk of death. ()

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A boy, 14 years old. After being treated with sulfonamide for his infection disease, he developed a fixed skin rash on the forehead. When the sulfonamide was stopped, the skin rash disappeared. Several months later, the boy got infected and took sulfonamide again. The similar skin rash appeared on the boy’s forehead again. What is the relationship between sulfonamide and the skin rash? ()

A. The skin rash is certainly caused by sulfonamide.
B. The skin rash is probably caused by sulfonamide.
C. The skin rash is possibly caused by sulfonamide.
D. The skin rash is unlikely caused by sulfonamide.
E. Their relationship is unassessable.

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