Methods used to revert adult somatic cells to totipotent or pluripotent stem cells are:
A. somatic cell nuclear transfer (SCNT)
B. chromosome transfer
C. small molecule-mediated direct reprogramming
D. viral transduction-mediated direct reprogramming
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Membersofthe Klf familythatcaninduceiPSCformationinclude:
A. Klf1
B. Klf2
C. Klf4
D. Klf5
Members ofthe Sox family that can induce iPSC formation include:
A. Sox1
B. Sox2 & Sox3
C. Sox15
D. Sox18
Stem cells have the potential to treat:
A. stroke
B. brain trauma
C. learning defects
D. Alzhermer's disease
Challenges & problems in generating iPSCs are:
A. low efficiency
B. genomic insertion
C. tumorigenicity
D. incomplete reprogramming