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Infection with herpes simplex virus, a common human pathogen, is best described by which of the following statements?

A. The CNS and visceral organs are usually involved
B. It rarely recurs in a host who has a high antibody titer
C. It can be reactivated by emotional disturbances or prolonged exposure to sunlight
D. Initial infection usually occurs by intestinal absorption of the virus

The most sensitive test for the diagnosis of herpes simplex meningitis in a newborn infant is

A. HSV IgG antibody
B. HSV polymerase chain reaction (PCR)
C. HSV culture
D. Tzanck smear

Cytomegalovirus (CMV) infection is common. Which one of the following statements best characterizes CMV?

A. It can be transmitted across the placental barrier
B. While a common infection, CMV is almost always symptomatic
C. The CMV can be cultured from red blood cells of infected patients
D. Unlike other viral infection, CMV is not activated by immunosuppressive therapy

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