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Additional operations such as grinding, homogenization, or leaching, required to recover products from solid sources such as plant and animal tissues, are usually included in this group.
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Solvent extraction, adsorption, ultrafiltration, and precipitation are some of the unit operations involved.
For most products, water is the chief impurity and isolation steps are designed to remove most of it, reducing the volume of material to be handled and concentrating the product.
Examples of operations include affinity, size exclusion, reversed phase chromatography, crystallization and fractional precipitation.
Crystallization, desiccation, lyophilization and spray drying are typical unit operations.
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