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阅读下面这篇短文，短文后有2项测试任务：(1)第23～26题要求从所给的6个选项中为规定段每段选择1个正确的小标题；(2)第27～30题要求从所给的6个选项中选择4个正确选项，分别完成每个句子。 A new drug shows hope of conquering a form of leukemia by targeting the misbehaving cells two summers ago Douglas Jenson was so wiped out from battling chronic myelogenous(骨髓性的) leukemia(白血病) (CML) that he could do little more than sit by his window; watching the numbers on a thermometer rise and fall with the sun. Today thanks to an experimental drug called STI571 (brand name: Glivec), Jenson 67, is biking in Oregon and planning a trip to the Caribbean. "I feel wonderful," he says.2. So do his doctors. STI571, a "smart bomb" drug that targets leukemia cells without harming healthy ions, first made headlines last year when researchers announced that white blood counts had returned to normal in 31 out of 31 patients who had taken the pill. Last week scientists were hack reporting new data on just over 1000 patients. In one trial, more than 90 % of 532 people on the drug saw counts return to normal. And under microscopic examination, 28 percent showed no evidence of cancer left in their bone marrow.3. The drug even helped, although not as dramatically, some patients in the final "blast" phase of the disease, when survival is measured in months. STI571"has ignited the cancer-research field", says Dr Brian Druker, an Oregan Health Sciences University researcher who developed the drug with manufacturer Novartis.4. CML, diagnosed in 5100 Americans every year, is triggered when two chromosomes swap fragments of genetic information. CML starts with the mistaken swap of genes between two chromosomes. The resulting "Philadelphia chromosome" produces the mutant Bcr-Abl protein. Bcr-Abl transfers a phosphate from the chemical messenger ATP to other proteins. They initiate a flawed signal to white blood cells to replicate incessantly.5. STI571 returns blood counts back to normal for those patients with chronic myelogenous leukemia(CML) in a "smart bomb way" by targeting the protein that sends the message to make the white blood cells. Bone marrow transplants can work extremely well, but they’ re applicable only for a minority of patients; otherwise, standard treatment is the injectable drug interferon. Many patients, however, cannot tolerate the adverse effects, which include severe fatigue, weight loss and depression. The new pill works by deactivating the cancer cells’ growth signal. Side effects- nausea, eye puffiness, muscle aches have been relatively mild so far. Interferon treatment causes______.
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软件开发工具一体化的困难何在今后发展前途如何
Directions: Read the following text. Choose the best word(s) for each numbered blank. Women often (1) that dating is like a cattle (2) , and a paper just published in Biology Letters by Thomas Pollet and Daniel Nettle of Newcastle University, in England, suggests they are (3) . They have little cause for complaint, however, because the paper also suggests that in this particular market, it is (4) who are the buyers. Mr. Pollet and Dr. Nettle were looking for (5) to support the contention that women choose men of (6) status and resources, as well as good looks. That may sound common sense, but it was often (7) by social scientists until a group of researchers who called themselves evolutionary psychologists started investigating the matter two decades ago. Since then, a series of experiments in laboratories have supported the contention. But as all zoologists know, (8) can only tell you so much. Eventually, you have to look at (9) populations. And that is what Mr. Pollet and Dr. Nettle have done. They have examined data from the 19t0 census of the United States of America and discovered that marriage is, indeed, a market. Moreover, as in any market, a (10) of buyers means the sellers have to have particularly attractive goods on (11) if they are to make the exchange. The advantage of picking 1910 was that America had not yet settled down, demographically speaking. Though the long-colonized eastern states had a sex (12) of one man to one woman, or thereabouts, in the rest of the country the old adage "go west, young man" had resulted in a (13) of males. Mr. Pollet and Dr Nettle were thus able to see just how picky women are, (14) the chance. (15) looking at the whole census, the two researchers relied on a sample of one person in 250. They then (16) the men in the sample a socioeconomic status score between zero and 96, on a scale drawn up in 1950 (which was as close to 1910 as they could get). They showed that in states where the sexes were equal in number, 56% of low status men were married by the age of 30, (17) 60% of high status men were. Even in this case, then, there are women who would prefer to remain (18) rather than marry a deadbeat. When there were 110 men for every 100 women (as, for example, in Arizona), the women got really (19) . In that case only 24% of low-status men were married by 30 compared with 46% of high-status men. As the men went west, then, so did their (20) opportunities.
试述硅肺基本病变及分期。
Part BDirections: In the following article, some sentences have been removed. For Questions 41-45, choose the most suitable one from the list A-G to fit into each of the numbered blanks. There are two extra choices, which do not fit in any of the blanks. Fields across Europe are contaminated with dangerous levels of the antibiotics given to farm animals. The drugs, which are in manure sprayed onto fields as fertilizers, could be getting into our food and water, helping to create a new generation of antibiotic-resistant "superbugs". The warning comes from a researcher in Switzerland who looked at levels of the drugs in farm slurry. 41．______ Some 20,000 tons antibiotics are used in the European Union and the US each year. More than half are given to farm-animals to prevent disease and promote growth. But recent research has found a direct link between the increased use of these farmyard drugs and the appearance of antibiotic-resistant bugs that infect people. 42．______But far more of the drugs end up in manure than in meat products, says Stephen Mueller of the Swiss Federal Institute for Environmental Science and Technology in Dubendorf. And manure contains especially high levels of bugs that are resistant to antibiotics, he says. With millions of tons of animals manure spread onto fields of crops such as wheat and barley each year, this pathway seems an equally likely route for spreading resistance, he said. 43．______They could also be leaching into tap water pumped from rocks beneath fertilized fields. Mueller is particularly concerned about a group of antibiotics called sulphonamides. They do not easily degrade or dissolve in water. His analysis found that Swiss farm manure contains a high percentage of sulphonamides; each hectare of field could be contaminated with up to 1 kilogram of the drugs. 44．______But vets are not treating the issue seriously. There is growing concern at the extent to which drugs, including antibiotics, are polluting the environment. 45．______ [A] The drugs contaminate the crops, which are then eaten. [B] This concentration is high enough to trigger the development of resistance among bacteria. [C] Animal antibiotics is still an area to which insufficient attention has been paid. [D] Most researchers assumed that humans become infected with the resistant strains by eating contaminated meat. [E] There is no doubt that the food and drink is always important to the health. [F] Many drugs given to humans are also excreted unchanged and are not broken down by conventional sewage treatment. [G] His findings are particularly shocking because Switzerland is one of the few countries to have banned antibiotics as growth promoters in animal feed.
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