题目内容

Which antibiotics can not be inactivated by beta- lactamase produced by bacteria?

A. penicillin,
B. streptomycin,
C. vacomycin,
D. Cephalosporin.

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Which type of point mutation in chromosomal gene is less likely to alter pore proteins to prevent the entry of drug into cytoplasm.

A. silent mutation;
B. missense mutation,
C. nonsense mutation;
D. Frameshift insertion.

Which protein with mutations in its gene could not inducedrug resistance?

A. porin in the outer membrane;
B. P12 of 30S ribosome ,
C. β-unit of RNA polymerase ;
D. lipoprotein in cell wall.

Which mechanism will confer sulfonamide resistance in thebacteria?

A. Bacteria absorb folic acid from the environment;
Bacteria alter P12 of 30S ribosome ,
C. Bacteria with mutatedβ-unit of RNA polymerase ;
D. Bacteria produce beta-lactamases.

Which statement about efflux pumps of bacteria is not right?

An efflux pump is a membrane active protein.
B. An efflux pump works without consumption of ATP.
C. Efflux pumps can pump more than one type of antimicrobials out of a cell.
D. Efflux pumps can confer multi-drug resistance to bacteria.

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