超星 - 逆转录病毒--章节练习

单选题

Regarding HIV which of the following is not true

A. It is a DNA retrovirus
B. Contains reverse transcriptase
C. May infect host CD4+ cells other than T-lymphocytes
D. Causes a reduction in host CD4+ cells at late stage of disease

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单选题

HIV can be detected and confirmed by

A. Polymerase chain reaction (PCR)
B. Reverse transcriptase - PCR
C. Real time PCR
D. Mimic PCR

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单选题

HIV-1 encodes an envelope glycoprotein, gp120. This protein

A. Causes membrane fusion
Binds to the viral coreceptor on the cell surface
C. Is highly conserved among different isolates
D. Fails to elicit neutralizing antibody
E. Induces chemokine production

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单选题

An HIV-positive patient asks you if you can tell him the chances of him progressing to symptomatic AIDS. Which one of the following tests would be most useful?

A. CD4 lymphocyte count
B. HIV antibody test
C. HIV RT-PCR
D. HIV p24 antigen

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单选题

The latest and most effective therapy for AIDS patients includes azidothymidine (AZT), dideoxyinosine (DDI), and saquinavir or similar agents. Use of these three drugs would inhibit which of the following viral processes?

A. RNase, DNase
B. gp120 formation
C. p24 antibody expression
D. Reverse transcriptase andprotease

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单选题

An HIV-positive patient prior to being treated with AZT, DDI, and saquinavir has a CD4 lymphocyte count and an HIV RNA viral load test done. Results are as follows:CD4: 50 CD4 lymphocytes per microliterHIV RNA: 750,000 copies per ml Which of the following statements best describes the above patient?

A. This patient is no longer in danger of opportunistic infection
B. The 5-year prognosis is excellent
C. The patient's HIV screening test is most likely negative
D. The viral load of 750,000 copies per ml suggests that the patient will respond to triple therapy

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