Regarding HIV which of the following is not true
A. It is a DNA retrovirus
B. Contains reverse transcriptase
C. May infect host CD4+ cells other than T-lymphocytes
D. Causes a reduction in host CD4+ cells at late stage of disease
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HIV can be detected and confirmed by
A. Polymerase chain reaction (PCR)
B. Reverse transcriptase - PCR
C. Real time PCR
D. Mimic PCR
HIV-1 encodes an envelope glycoprotein, gp120. This protein
A. Causes membrane fusion
Binds to the viral coreceptor on the cell surface
C. Is highly conserved among different isolates
D. Fails to elicit neutralizing antibody
E. Induces chemokine production
An HIV-positive patient asks you if you can tell him the chances of him progressing to symptomatic AIDS. Which one of the following tests would be most useful?
A. CD4 lymphocyte count
B. HIV antibody test
C. HIV RT-PCR
D. HIV p24 antigen
The latest and most effective therapy for AIDS patients includes azidothymidine (AZT), dideoxyinosine (DDI), and saquinavir or similar agents. Use of these three drugs would inhibit which of the following viral processes?
A. RNase, DNase
B. gp120 formation
C. p24 antibody expression
D. Reverse transcriptase andprotease
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