Numerous studies have demonstrated that human mesenchymal stem cells (MSCs) can:
A. avoid allorecognition
B. interfere with dendritic cell function
C. interfere with T-cell function
D. generate a local immunosuppressive microenvironment by secreting cytokines
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_______________________________havebeenidentifiedascrucialtranscriptionalregulatorsinvolvedintheinductionprocessofsomaticcellsintoiPSCs.
A. Oct-3/4(Pou5f1)
B. Sox1
C. Sox2&Sox3
D. Sox15
________________________ canincrease the induction efficiency for somatic cells to iPSCs.
A. the Klf family (Klf1, Klf2, Klf4, & Klf5)
B. the Myc family (c-myc, L-myc, & N-myc)
C. Nanog
D. LIN28
Methods used to revert adult somatic cells to totipotent or pluripotent stem cells are:
A. somatic cell nuclear transfer (SCNT)
B. chromosome transfer
C. small molecule-mediated direct reprogramming
D. viral transduction-mediated direct reprogramming
Membersofthe Klf familythatcaninduceiPSCformationinclude:
A. Klf1
B. Klf2
C. Klf4
D. Klf5