题目内容

Which one of the following is the best explanation for the selective action of acyclovir (acycloguanosine) in herpes simplex virus-infected cells ?

Acyclovir binds specifically to viral receptors only on the surface of the HSV-infected cell
B. Acyclovir is phosphorylated by a virus-encoded phosphokinase only within HSV-infected cells
C. Acyclovir selectively inhibits the RNA polymerase in theHSV virion
D. Acyclovir specifically blocks the matrix protein of HSV, thereby preventing release of progeny HSV

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The serum of a newborn infant reveals a 1:32 CMV titer. The child is clinically asymptomatic. Which of the following courses of action would be advisable?

A. Repeat the CMV titer immediately
B. Wait 6 months and obtain another titer on the baby
C. Obtain a CMV titer from all siblings
D. Obtain an anti-CMV IgM titer from the mother
E. Obtain an anti-CMV IgM titer from the baby

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Adults who have had varicella as children occasionally suffer a recurrent form of the disease, shingles. The agent causing these diseases is member of which of the following viral families?

A. Herpesvirus
B. Poxvirus
C. Reoviruse
D. Paramyxovirus

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An immunocompromised person with history of seizures had an MRI that revealed a temporal lobe lesion. Brain biopsy results showed multinucleated giant cells with intranuclear inclusions. The most probable cause of the lesion is

A. Hepatitis C virus
B. Herpes simplex virus
C. Listeria monocytogenes
D. Coxsackievirus
E. Parvovirus

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中枢神经系统( )

A. 指端脑、间脑、小脑和脑干
B. 包括脑和脊髓
C. 指脊神经和脑神经
D. 指脊髓和脑干

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