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The iPSC technology was pioneered by Professor Shinya Yamanaka's lab in Kyoto, Japan in 2006, and he used four transcription factors including _______, _______, ________, and ________ in his first study.
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List 4 fundamental ethical principles for stem cell research: __________________, ___________________, ______________________, and _______________________.
Stochastic differentiation refers to thatwhen one stem cell develops into two differentiated daughter cells, another stem cell undergoes mitosis & produces two stem cells identical to the original.
In adult organisms, stem cells and progenitor cells act as a repair system for the body, replenishing adult tissues. In some organs, such as the gut & bone marrow, stem cells regularly divide to repair & replace worn out or damaged tissues. In other organs, however, such as the pancreas & the heart, stem cells only divide under special conditions.
Obligatory asymmetric replication refers to that a stem cell divides into one mother cell that is identical to the original stem cell, & another daughter cell that is differentiated.
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