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Risk-benefit evaluations are vital to ensuring ethical clinical research. Using a systematic approach can not help to protect subjects while allowing valuable and appropriate research.
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The World Medical Association (WMA) has developed the Declaration of Helsinki as a statement of ethical principles for medical research involving human subjects and animals, including research on identifiable human material and data.
TheDeclarationofHelsinki(2013, Article 5)byWMAdeclaresthat,"Medicalprogressisnotbasedonresearchthatultimatelymustincludestudiesinvolvinghumansubjects".
TheDeclarationofHelsinki(2013, Article 6)byWMAdeclaresthat,"The primary purpose of medical research involving human subjects is to understand the causes, development and effects of diseases and improve preventive, diagnostic and therapeutic interventions (methods, procedures and treatments). Even the best proven interventions must be evaluated continually through research for their safety, effectiveness, efficiency, accessibility and quality".
TheDeclarationofHelsinki(2013,Article 11)byWMAdeclaresthat,"Medical research should be conducted in a manner that minimises possible harm to the environment".
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