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Despite thorough testing and appropriate management practices, the introduction of agents into a facility or parts of it can always be avoided. It is therefore important that animals in breeding units as well as in experimental units are regularly monitored to confirm their status.
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Gnotobiotic animals play a minor role and are at present often used for animal experiments.
By the laws, each institution in the US must have an Institutional Animal Care and Use Committee (IACUC) to oversee and evaluate the institution's animal program to assure compliance with all the regulations.
The Animal Welfare Act 2006 in the UK contains the general laws relating to animal welfare. It is not an offence to cause unnecessary suffering to any animal.
The Universal Declaration on Animal Welfare is a proposed inter-governmental agreement to recognize that animals are sentient, to prevent cruelty and reduce suffering, and to promote standards on the welfare of animals such as farm animals, companion animals, animals in scientific research, draught animals, wildlife and animals in recreation.
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