Which of the following statements about isolation of influenza viruses is correct?
A. Primary influenza virus isolates grow readily in cell culture
B. Diagnosis of an influenza virus infection can only be made by isolating the virus
C. Isolation of virus can help determine the epidemiology of the disease
D. Isolation of influenza virus is done using newborn mice.
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A 2-month-old infant developed a respiratory illness that the pediatrician diagnosed as bronchiolitis（细支气管炎）. The most likely cause of the disease is
A. Parainfluenza virus type 4
B. Respiratory syncytial virus
C. Influenza virus
D. Metapneumovirus
E. Measles virus
A 20-month-old boy had an illness characterized by fever, irritability, conjunctivitis, and a brick-red rash initially on the face but spreading downward and outward. At age 9 years, the boy had a gradual onset of severe, generalized neurologic deterioration. Subacute sclerosing panencephalitis (SSPE) was diagnosed. Which of the following statements about SSPE is correct?
A. Rapidly progressive deterioration of brain function occurs
B. The disease is a rare, late complication of rubella infection
C. The incidence of the disease is rising since the introduction of MMR vaccine
D. High titers of measles antibody are found in cerebrospinal fluid
E. Defective varicella-zoster virus is present in brain cells.
Each of the following statements concerning measles vaccine is correct except
A. The vaccine should not be given before 15 months of age because maternal antibodies can prevent an immune response
B. Virus in the vaccine contains only one serotype
C. The vaccine should not be given at the same time as the mumps vaccine because the immune system cannot respond to two viral antigens given simultaneously
D. The vaccine contains live, attenuated virus.
Each of the following statements concerning rubella is correct except
A. Congenital abnormalities occur primarily when a pregnant woman is infected during the first trimester
B. Women who say that they have never had rubella can, nevertheless, have neutralizing antibody in their serum
C. In a 6-year-old child, rubella is a mild, self-limited disease with few complications
D. Acyclovir is effective in the treatment of congenital rubella syndrome
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