Adult stem cells include:
A. hematopoietic stem cells
B. mesenchymal stem cells
C. neural stem cells
D. epithelial stem cells
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Shinya Yamanaka in Kyoto of Japanused the transcription factors _____________________________ to reprogram mouse fibroblast cells into pluripotent cells.
A. Oct3/4
B. Sox2
C. c-Myc
D. Klf4
Numerous studies have demonstrated that human mesenchymal stem cells (MSCs) can:
A. avoid allorecognition
B. interfere with dendritic cell function
C. interfere with T-cell function
D. generate a local immunosuppressive microenvironment by secreting cytokines
_______________________________havebeenidentifiedascrucialtranscriptionalregulatorsinvolvedintheinductionprocessofsomaticcellsintoiPSCs.
A. Oct-3/4(Pou5f1)
B. Sox1
C. Sox2&Sox3
D. Sox15
________________________ canincrease the induction efficiency for somatic cells to iPSCs.
A. the Klf family (Klf1, Klf2, Klf4, & Klf5)
B. the Myc family (c-myc, L-myc, & N-myc)
C. Nanog
D. LIN28