题目内容

Shinya Yamanaka in Kyoto of Japanused the transcription factors _____________________________ to reprogram mouse fibroblast cells into pluripotent cells.

A. Oct3/4
B. Sox2
C. c-Myc
D. Klf4

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Numerous studies have demonstrated that human mesenchymal stem cells (MSCs) can:

A. avoid allorecognition
B. interfere with dendritic cell function
C. interfere with T-cell function
D. generate a local immunosuppressive microenvironment by secreting cytokines

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_______________________________havebeenidentifiedascrucialtranscriptionalregulatorsinvolvedintheinductionprocessofsomaticcellsintoiPSCs.

A. Oct-3/4(Pou5f1)
B. Sox1
C. Sox2&Sox3
D. Sox15

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________________________ canincrease the induction efficiency for somatic cells to iPSCs.

A. the Klf family (Klf1, Klf2, Klf4, & Klf5)
B. the Myc family (c-myc, L-myc, & N-myc)
C. Nanog
D. LIN28

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Methods used to revert adult somatic cells to totipotent or pluripotent stem cells are:

A. somatic cell nuclear transfer (SCNT)
B. chromosome transfer
C. small molecule-mediated direct reprogramming
D. viral transduction-mediated direct reprogramming

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Shinya Yamanaka in Kyoto of Japanused the transcription factors _____________________________ to reprogram mouse fibroblast cells into pluripotent cells.

A. Oct3/4 B. Sox2 C. c-Myc D. Klf4

Numerous studies have demonstrated that human mesenchymal stem cells (MSCs) can:

_______________________________havebeenidentifiedascrucialtranscriptionalregulatorsinvolvedintheinductionprocessofsomaticcellsintoiPSCs.

________________________ canincrease the induction efficiency for somatic cells to iPSCs.

Methods used to revert adult somatic cells to totipotent or pluripotent stem cells are:

A. Oct3/4
B. Sox2
C. c-Myc
D. Klf4