In the book The Principles of Humane Experimental Technique, published in 1959, Russell and Burch proposed the concept of the 3Rs.
A. 1949
B. 1953
C. 1955
D. 1959
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________________ refers to methods which avoid or replace the use of animals in an area where animals would otherwise have been used.
A. Refinement
B. Reduction
C. Replacement
D. Redoing
________________ refers to any strategy that will result in fewer animals being used.
A. Reduction
B. Refinement
C. Replacement
D. Rethinking
______________ refers to the modification of husbandry or experimental procedures to minimize pain and distress.
A. Reduction
B. Replenishment
C. Replacement
D. Refinement
Inthereductiondimensionthereisa__________ofappropriatenumbersofanimals,belowandabovewhichtheexperimentbecomesmeaninglessandunethical.
A. hole
B. gap
C. tool
D. window