Adultstemcellshavebeenidentifiedinmanyorgans&tissues,including:
A. heart
B. gut
C. liver
D. ovarian epithelium & testis
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Adult stem cells include:
A. hematopoietic stem cells
B. mesenchymal stem cells
C. neural stem cells
D. epithelial stem cells
Shinya Yamanaka in Kyoto of Japanused the transcription factors _____________________________ to reprogram mouse fibroblast cells into pluripotent cells.
A. Oct3/4
B. Sox2
C. c-Myc
D. Klf4
Numerous studies have demonstrated that human mesenchymal stem cells (MSCs) can:
A. avoid allorecognition
B. interfere with dendritic cell function
C. interfere with T-cell function
D. generate a local immunosuppressive microenvironment by secreting cytokines
_______________________________havebeenidentifiedascrucialtranscriptionalregulatorsinvolvedintheinductionprocessofsomaticcellsintoiPSCs.
A. Oct-3/4(Pou5f1)
B. Sox1
C. Sox2&Sox3
D. Sox15