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Test 15
判断题
Any refinement to animal experiments to improve animal welfare requires scientific validation to ensure the refinements are truly beneficial for the animals and do detract from the scientific integrity of the results. This is to say that in order to get a comprehensive picture, one should use scientific method to prove both efficacy and 'safety' of a refinement.
A. 对
B. 错
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判断题
A EU report called for a cost-benefit analysis as an integral part of any ethical review. The report states that "Before a license is issued, an ethical and animal-welfare assessment must be carried out setting limits to the level of stress to which the animals may be subjected. Even if it can be shown that certain experiments may be of benefit to animals or humans, they should not be authorized if the stress on the animals used in the experiment exceeds the maximum level."
A. 对
B. 错
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判断题
Reduction alternatives refer to any strategy that will result in more animals being used to obtain sufficient data to answer the research question, or in maximizing the information obtained per animal and thus potentially limiting or avoiding the subsequent use of additional animals, without compromising animal welfare.
A. 对
B. 错
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判断题
Many agents, although clinically silent, were shown to influence physiological or immunological functions. Research complications occurred infrequently and resulted in the need to eliminate also those agents that cause clinically-silent infections, and to monitor colonies for the presence or absence of such microorganisms.
A. 对
B. 错
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判断题
It is sufficient that laboratory animals are free of disease, it is essential that they are free of agents that may have impact on the health of animals (and humans) or on the results of animal experiments.
A. 对
B. 错
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判断题
There is no doubt that research complications due to overt infectious disease are insignificant and that animals with clinical signs of disease should not be used for scientific experiments.
A. 对
B. 错
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判断题
All infections, apparent or inapparent, are likely to increase biological variability and hence result in a decrease in animal use.
A. 对
B. 错
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判断题
Infected animals may show altered behaviour, suppressed body weight, or reduced life expectancy which may, for example, influence the tumor rate in a population.
A. 对
B. 错
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判断题
Animals from commercial breeders are usually monitored carefully, and insufficient information on their health status is in most cases available.
A. 对
B. 错
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判断题
Despite thorough testing and appropriate management practices, the introduction of agents into a facility or parts of it can always be avoided. It is therefore important that animals in breeding units as well as in experimental units are regularly monitored to confirm their status.
A. 对
B. 错
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