超星 - Test 3 - 查题吧

判断题

It is possible to collect amniotic stem cells for donors or for autologuous use: the first US amniotic stem cells bank was opened in 2009 in Littleton, MA, by Biocell Center Corporation & collaborates with various hospitals & universities all over the world.

A. 对
B. 错

判断题

The induced pluripotent stem cell(iPSC) technology was pioneered by Shinya Yamanaka's lab in Kyoto, Japan, who showed in 2006 that the introduction of four specific genes encoding transcription factors could convert adult cells into pluripotent stem cells. He was awarded the 2012 Nobel Prize along with Sir John Gurdon "for the discovery that mature cells can be reprogrammed to become pluripotent".

A. 对
B. 错

判断题

Amniotic stem cells are multipotent and can differentiate in cells of adipogenic, osteogenic, myogenic, endothelial, hepatic, & also neuronal lines.

A. 对
B. 错

判断题

Induced pluripotent stem cells (iPSCs) are useful tools for drug development & modeling of diseases, & scientists hope to use them in transplantation & regenerative medicine. They represent a single source of cells that could be used to replace those lost to damage or disease.

A. 对
B. 错

判断题

Induced pluripotent stem cells (iPSCs) differ from ESCs. They share many similar properties, such as pluripotency & differentiation potential, the expression of pluripotency genes, epigenetic patterns, embryoid body, & teratoma formation, & viable chimera formation, but there are many differences within these properties.

A. 对
B. 错

判断题

The chromatin of Induced pluripotent stem cells (iPSCs) appears to be more "closed" or methylated than that of embryonic stem cells (ESCs).

A. 对
B. 错

判断题

Multipotent stem cells are found in amniotic fluid. These stem cells are very active, expand extensively without feeders and are not tumorigenic.

A. 对
B. 错

判断题

25% of mice transplanted with c-myc-induced iPSCs developed lethal teratomas. N-myc & L-myc have been identified to induce instead of c-myc with similar efficiency.

A. 对
B. 错

判断题

The low induction efficiency may reflect the need for precise timing, balance, & absolute levels of expression of the reprogramming genes. It may also suggest a need for rare genetic and/or epigenetic changes in the original somatic cell population or in the prolonged culture. Depletion of Mbd3 improves reprogramming efficiency.

A. 对
B. 错

判断题

Reprogramming of adult cells to obtain iPSCs never increase the risk of tumorigenecity.

A. 对
B. 错

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