超星 - Test 6 - 查题吧

单选题

Contemporary understanding of synthetic biology was given by ____________ geneticist Wacław Szybalski in a panel discussion during Eighteenth Annual "OHOLO" Biological Conference on Strategies for the Control of Gene Expression in 1973 Zichron Yaakov, Israel.

A. German
B. Russian
C. English
D. Polish

单选题

A notable advance in synthetic biology occurred in _______, when two articles in Nature by Michael B. Elowitz et al. at CalTech and Stanislas Leibler et al. at the Rockefeller University discussed the creation of synthetic biological circuit devices of a genetic toggle switch and a biological clock by combining genes within E. coli.

A. 1995
B. 1998
C. 2000
D. 2005

单选题

In _______, researchers at Washington University reported synthesis of the 9.6 kbp (kilo base pair) hepatitis C virus genome from chemically synthesized 60 to 80-mers.

A. 1995
B. 1997
C. 2000
D. 2003

单选题

In _______, researchers at SUNY Stony Brook succeeded in synthesizing the 7,741 base poliovirus genome from its published sequence, producing the second synthetic pathogen genome. This took about two years of work.

A. 1998
B. 2000
C. 2002
D. 2004

单选题

Scientists engineered yeast by increasing farnesyl pyrophosphate production and introducing the amorphadiene synthase and cytochrome P450 genes from Artemisia annua to efficiently convert simple sugars to artemisinic acid in ______.

A. 2000
B. 2003
C. 2006
D. 2010

单选题

In ______, a minimal prokaryotic genome, the chromosome of M. genitalium JCVI-1.0, was successfully chemically synthesized and assembled. In the same year, one-step assembly of 25 chemical DNA fragments into an intact M. genitalium genome was achieved in yeast by the same research group.

A. 2000
B. 2004
C. 2008
D. 2012

单选题

A pair of synthetic gene circuits that count events — a long-stated goal for circuit engineers — was reported in _______. For one of these counter circuits, recombinase-mediated DNA rearrangement was used to create permanent memory of an event, and a similar strategy was later used to engineer a full set of recombinase-based logic gates.

A. 2004
B. 2006
C. 2009
D. 2012

单选题

In ______, the first synthetic yeast genome project (Sc. 2.0 project) was launched to redesign and chemically synthesize the entire S. cerevisiae genome.

A. 2000
B. 2005
C. 2009
D. 2013

单选题

In ______, the Royal Academy of Engineering in the United Kingdom released the report "Synthetic Biology: Scope, Applications and Significance." The report summarized the basic technologies and development status of synthetic biology and predicted the application impact on technology, economy, and society for the next 5, 10, and 25 years.

A. 1999
B. 2005
C. 2009
D. 2015

单选题

In ______, John Craig Venter (1946- ) et al. reported their assembly of a synthetic M. Mycoides genome in yeast. Venter and colleagues used breakthrough DNA-assembly techniques to create a viable bacterial cell that was controlled by a chemically synthesized genome. Synthesized DNA cassettes were assembled by in vivo recombination in yeast to recreate the M. mycoides genome, which was then transplanted into a recipient bacterial cell, resulting in viable bacteria that contained only the synthesized genome.

A. 2004
B. 2006
C. 2008
D. 2010

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